WHO expert consultation on serotype composition of pneumococcal conjugate vaccines for use in resource-poor developing countries, 26-27 October 2006, Geneva.
نویسنده
چکیده
Pneumococcal conjugate vaccines induce serotype specific protection, with cross-protection seen between serotypes within certain serogroups. Though most serious pneumococcal infections are caused by relatively small number of serotypes, choices need to be made on the serotypes to be included in the vaccine because of the complexity and cost related to developing and producing vaccines with increasing number of serotypes. The choice is rendered difficult because of differences in the distribution of serotypes causing serious disease between different geographic regions and age groups as well as changes over time. The World Health Organization convened an expert consultation to formulate a data-driven approach to determine the minimum or optimal formulation of pneumococcal conjugate vaccines, particularly keeping in mind the needs of developing countries as well as the epidemiologic, regulatory, formulation and manufacturing issues involved. The deliberations and conclusions of this meeting are summarized in this report.
منابع مشابه
Molecular and epidemiological trend of sapovirus, and astrovirus infection in Japan.
1. World Health Organization. Pneumococcal conjugated vaccine for childhood immunization. Wkly Epidemiol Rep 2007;12:93–104. 2. Clinical and Laboratory Standards Institute, Institute CaLS. Methods for Dilution Antimicrobial Susceptibility for Bacteria that Grow Aerobically, Approved Standard M100-S16, 2006. 3. Inoue M, Farrell DJ, Kaneko K, et al. Antimicrobial susceptibility of respiratory tra...
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ورودعنوان ژورنال:
- Vaccine
دوره 25 36 شماره
صفحات -
تاریخ انتشار 2007